If someone is described as beingat their wit's end. It means they are:

• At one's wit's end
English Meaning: at a loss for a means of solving a problem / confused / puzzled.
Bangla Meaning: দিশেহারা / হতবুদ্ধি।

Ex. Sentence: I am at one's wit's end , I don't know how to help him.
Bangla Meaning: আমি হতবুদ্ধি হয়ে গেছি, জানিনা তাকে কিভাবে সহযোগিতা করতে পারি।

Source: Lecture.