He’ll need to use all his unusual methods and screwball wiles to complete his mission. Here 'wiles' refers to -

• Wile (noun)
English Meaning: Skill and ways of tricking people into doing what you wantskill and ways of tricking people into doing what you want
Bangla Meaning: (সাধারণত plural) কূটকৌশল; চাতুরী; শয়তানি:

Synonyms: Trickery (ছলচাতুরী করা), Cunning (কূটকৌশল), Cheating (ধান্দাবাজি), Artifice (চালাকি), Betraying (প্রতারণা করা)।
Antonyms: Frankness (নির্ভীকতা), Honesty (সততা), Openness (স্বচ্ছতা), Candidness (সরলতা), Straightness (অকপটতা) Sincerity (আন্তরিকতা; সততা) Ingenuousness (নিষ্কাপট্য; অকপটতা; সরলচিত্ততা; সারল্য)

• Example Sentence:
- He’ll need to use all his unusual methods and screwball wiles to complete his mission.
- His wit and wile has made him one of the sharpest politicians in the Cabinet.
- The wiles of the Devil. She fell a victim to the wiles of that unscrupulous rogue.

Source:
1. Accessible Dictionary by Bangla Academy.
2. Cambridge Dictionary.
3. Merriam-webster Dictionary.
4. Website Lecture.